Biomedical Laboratory Science

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Showing posts with label Bioengineering. Show all posts
Showing posts with label Bioengineering. Show all posts

Sunday, September 25, 2016

Swarms of Magnetic Bacteria Could be Used to Deliver Drugs to Tumors

One of the biggest challenges in cancer therapy is being able to sufficiently deliver chemotherapy drugs to tumors without exposing healthy tissues to their toxic effects.

Researchers funded in part by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs. They reported their results in the August 2016 issue of Nature Nanotechnology.


Illustration showing magnetic bacteria delivering drugs to a tumor.
Source: LabManager

Friday, May 13, 2016

A Laboratory for Empowerment

Though women earn 50 percent of degrees in science and engineering, they only represent 27 percent of the workforce in those fields. The UCSD Guardian investigates women’s representation in STEM at UCSD, as well as the steps the university is taking to increase their presence.

Seventy-seven cents to every man’s dollar. It’s a statistic often thrown around when discussing the oppression of women in the United States, but less often understood. The number does not come from comparing one male engineer’s salary to that of a female engineer’s. Instead, 77 cents to every one male-earned dollar is a statistic that compares the total income generated by men in the U.S. to the total income generated by American women. It’s a statistic that reveals that, on average, women are employed in lower-paying careers than men are. It’s not that female engineers are being paid 23 percent less than their male counterparts. It’s that there aren’t as many female engineers as male engineers to begin with; considering that, according to Payscale.com, the top 14 paying majors in the U.S. are in science, technology, engineering and math, this is a huge missed opportunity.

This is where STEM comes in. It’s a little acronym that represents a big conversation in today’s society. According to the U.S. Department of Commerce, in 2011, women held nearly half the jobs in the U.S. economy, but filled less than a quarter of the country’s STEM-related positions. Although women today have far more opportunities in academia than in the past, there are still far more men occupying STEM-related jobs than women. According to a 2013 study compiled by the National Girls Collaborative Project, while women are earning 50 percent of bachelor’s degrees in science and engineering, only 27 percent of the science and engineering workforce is made up of women. With nearly half of science and engineering bachelor’s degrees going to women, one would expect women to be equally represented in the workforce, making these statistics surprising.

Saturday, April 2, 2016

Human Myocardium is Bioengineered on Native Heart ‘Scaffold’.

Heart cells have been successfully grown in a human heart stripped of all cellular components by scientists at the Massachusetts General Hospital.

Using detergent, scientists removed all cells and human leukocyte antigens from 73 human hearts. The ‘matrix’ of the heart was then repopulated with pluripotent stem cells induced to differentiate into cardiac muscle. The scientists behind the work hope to create cardiac muscle to repair damaged tissue.

Professor Jacques Guyette, from the Massachusetts General Hospital (MGH) and lead author of this study, said: “Regenerating a whole heart is most certainly a long-term goal that is several years away, so we are currently working on engineering a functional myocardial patch that could replace cardiac tissue damaged due a heart attack or heart failure.”

In 2008, Dr Harold Ott, also from the MGH, developed a procedure to strip all cells from organs, leaving just the ‘scaffolding’ behind. To date, his technique has been used on hearts, lungs, livers, pancreases and kidneys.

MicroRNA molecules were used to reprogramme adult skin cells to created induced pluripotent stem cells (iPSC). It is hoped this method, as well as being more efficient, will be less likely to encounter regulatory issues.

Read more: Human Myocardium is Bioengineered on Native Heart ‘Scaffold’.


Source: labnews; thedailybeast
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