Biomedical Laboratory Science

Saturday, September 17, 2016

Boosting the Immune System to Effect Repairs and Fight Disease

Applications from Regenerative Medicine to Gene Therapy to Antiviral Therapeutics Emphasize Self-Healing

Therapeutic interventions of various kinds try to improve the body’s capacity to defend, repair, and even cure itself. Interventions that attempt to enhance self-healing span cell-based therapy, gene therapy, small molecule drugs, biologics, and tissue engineering.

Advances in each of these areas are being followed by Allied Market Research, which has concluded that stem cell technologies look especially promising. For example, stem cell technologies are set to revolutionize the human ability to produce neural cells in abundance.

Source: genengnews

The Best Medicine Against Cholesterol And High Blood Pressure

Cholesterol is a waxy substance that comes from two sources: your body and food. Excess cholesterol can form plaque between layers of artery walls, making it harder for your heart to circulate blood.

Plaque can break open and cause blood clots. If a clot blocks an artery that feeds the brain, it causes a stroke. If it blocks an artery that feeds the heart, it causes a heart attack.

Heart disease, stroke and other cardiovascular diseases are among the leading cause of death and now kill more than 800,000 adults in the US each year. Two main reasons people have heart disease or stroke are high blood pressure and cholesterol.

Source: herb-cookbook

Why Does Alcohol Burn When You Drink It?

Anyone who's ever taken a shot of hard liquor can tell you: it burns on the way down. But it's not the alcohol itself that's burning your throat. Instead, the ethanol in the liquid is making your throat's VR1 heat receptors more sensitive, prompting them to perceive your own body temperature as hot. (Of course, this doesn't mean you should do shot after shot without fear of consequences.) Learn more about the science of alcohol with the videos below.

Here's Why Taking A Shot Of Tequila Burns Your Throat

Why Does Alcohol Burn When You Drink It? from SciShow
Source: curiosity

Without Saying A Word, This Short Six Minute Video Will Leave You Speechless!

The shock toward the meat business is a developing issue these days all around the world. Namely, its flaws have been revealed in numerous documentaries and books and have triggered a massive dissatisfaction among people.

The video below is a short fragment from a narrative called “Samsara”, which is an imaginative examination of the creation of advanced nourishment. It will provide fundamental data on pork, poultry, and cattle facilities, as well as a grocery store, followed by a view of the conditions in a fast food restaurant. It ends in a doctor’s office.

Source: herb-cookbook

Friday, September 16, 2016

Sister Donates Eggs To Gay Brother

The idea that families come in all shapes and sizes has never been more true with adoption, same-sex relationships and the introduction of new ways to conceive.

Writer Samuel Leighton-Dore, 25, spoke to Mirror Online about his decision for his sister to have his child - and has opened up about the negative response it has received.

Samuel, from Sydney, is in a relationship with photographer and designer Bradley Tennant but doesn't want to miss out on their baby having both of their family's genes.

As a compromise, his sister Bronte has agreed to donate her eggs so that the couple can have the family they've always wanted.

Cancer: Four-Stranded DNA Could Help Develop Targeted Treatments

By taking a closer look at four-stranded versions of DNA inside the genome of human cells, scientists have discovered some potential new avenues for targeted cancer treatments. They found that the quadruple helix structures occur in DNA regions that control genes, especially cancer genes.

The researchers, from the University of Cambridge in the United Kingdom, report their findings in the journal Nature Genetics.

Targeted cancer therapies are currently the focus of much research and development into new anticancer treatments.

They are an important area of precision medicine - where information about an individual patient's genes and proteins are used to prevent, diagnose, and treat disease.

The aim of targeted therapy is to attack cancer cells without affecting healthy cells.

'Tracking Bugs' Reveal Secret of Cancer Cell Metabolism

One of the hallmarks of cancer is a change in cellular metabolism, a series of chemical reactions so fundamental to life that their alteration makes cancer cells seem creepily malevolent.

Healthy cells take in blood sugar (glucose molecules), which they break down to extract energy. This happens in two phases—one phase that takes place in the cytoplasm and a subsequent phase that occurs inside cellular compartments called mitochondria.

Cancer cells are thought to mostly skip the mitochondrial phase, compensating for the energy they forgo by revving up the first phase and breaking down glucose rapidly to secrete large quantities of lactate—a form of partially digested glucose that has long been regarded as a "waste product.

Metabolism is nothing if not complicated. Some of the major metabolic pathways are shown in this
metro-style map.

How Does Alcohol Affect My Blood Sugar Levels?

It is not uncommon to enjoy a glass of wine with dinner or to have drinks after work with friends. Alcohol consumption is very prevalent in the United States.

According to the National Institute on Alcohol Abuse and Alcoholism, in 2014:
  • 87.6 percent of people age 18 and older reported drinking alcohol at some point in their lifetime
  • 71 percent reported drinking in the past year
  • 56.9 percent reported drinking in the past month
For many people, a glass of alcohol here and there does not pose a problem. For those with certain health conditions such as diabetes, however, alcohol can affect blood sugar levels and pose a health risk. It is important for them to understand what alcohol is and how it affects blood sugar levels.

The way that alcohol affects the body differs from person to person. People with diabetes and other
blood sugar-related illnesses must be extremely careful when consuming alcohol. Cocktails and
mixed drinks are full of sugar, so should be avoided by people with blood sugar problems.

Wednesday, September 14, 2016

Take This Vitamin And You Will NEVER Get Another Bite From A Mosquito Again!

Ah… summer. Longer days, sunny skies, sandy beaches… and mosquitoes. Lots and lots of mosquitoes.

For some, this isn’t too big of a deal, as mosquito repellent has been on the market since 1956.

But, if you’re like me at all and you not only want to stop smelling like the burnt remains of a chemical plant after using repellent, but also are scared of the adverse effects of DEET in sprays and are more prone to getting bit (seriously though, mosquitoes seemed to love me and only me at parties), then taking Vitamin B1 could be your saving grace.

Vitamin B1 (also known as thiamine) is an essential vitamin your body needs. It can be found in foods such as yeast, oatmeal, brown rice, asparagus, kale, liver and eggs and is important in fighting stress and boosting immunity.

Tuesday, September 13, 2016

Polycystic Ovary Syndrome and Fertility: What You Need to Know

Polycystic ovary syndrome or PCOS for short is a disorder that causes an imbalance in female sex hormones. The imbalance can lead to a variety of symptoms and also affect a woman's fertility.

To understand what PCOS is and how it affects a woman, it's helpful to learn a little about how the ovaries work.

Every month in women of childbearing age, tiny fluid-filled cysts called follicles develop on the surface of the ovary. One of the follicles will produce a mature egg, which is released from the ovary. Female sex hormones including estrogen cause the egg to mature and break through the follicle.

In women who have polycystic ovary syndrome, there is an imbalance in female sex hormones. The imbalance may prevent mature eggs from developing and being released. Without a mature egg, ovulation does not occur, which leads to infertility.

The imbalance in female hormones may prevent ovulation, leading to infertility. If showing any
symptoms of PCOS, it is wise to see a doctor in order to prevent further complications. Unless a
woman is trying to get pregnant, birth control pills may be used to correct the hormonal imbalance.

Monday, September 12, 2016

Five Signs Of Hormone Imbalance You Shouldn't Ignore

Be vigilant of these five signs of hormonal imbalance, from poor sleep to chronic acne.

Hormones affect everyone from birth to death, yet the word has a negative connotation. Most people use "raging hormones" to explain teenage angst, or "hormonal" to describe PMS in women, and maybe for good reason: hormonal symptoms have a lot to do with our lifestyle, diet, and environment.

Hormone problems are very common, so feeling like we're experiencing a hormonal balance, or a fluctuation in hormones, is not unusual.

Melanoma May Be Stoppable With Drug That Halts Cancer Cell Proliferation

A drug already being tested in people as a treatment for cancer appears to show great promise in halting melanoma skin cancer. The drug - called pevonedistat - works in a way differently than intended and could also be effective against other cancers.

So says a new study from the University of Virginia School of Medicine in Charlottesville that was published in the journal EBioMedicine.

Lead researcher Tarek Abbas, assistant professor of radiation oncology, says:

"In fact, the drug is very effective on all melanomas, including those for which an effective therapeutic is lacking."

Melanoma is an aggressive skin cancer that develops when melanocytes - the cells that give skin its color - mutate and become cancerous.

Melanoma is an aggressive skin cancer that develops when cells that give skin its color mutate and
become cancerous. The researchers say they have found a drug that may stop the cancer progressing.

Ten Interesting Facts About Body Temperature

Body temperature can be affected by various circumstances

In order to maintain a healthy metabolic process, our enzymes need to be functioning at a certain optimal temperature – 37°C or 98.6°F. Body temperature is the balance between heat loss and heat production.

Fortunately, we are able to maintain a healthy body temperature regardless of external outside temperature. For instance, putting a jacket on if you are cold or taking off your sweater if you feel yourself getting warm.

Sunday, September 11, 2016

'We Can Completely Reverse Alcohol Dependence'

Scientists have discovered a way to entirely remove the urge to drink alcohol compulsively in an animal model. The researchers hope that, with enough funding, a solution to this age-old problem might be on the horizon.

Alcohol has been brewed and consumed by humans for almost 10,000 years.

In 2014, 87.6 percent of Americans over the age of 18 reported that they had consumed alcohol at least once in their life.

Although commonly available, it is an incredibly addictive substance. In the United States, an estimated 16.3 million adults over the age of 18 have an alcohol use disorder, and around 88,000 people die from alcohol-related causes annually.

For these reasons, thousands of researchers are dedicated to understanding the causes behind a compulsive need to drink alcohol and ways in which it might be curbed.

Could alcoholism finally be on the way out?

Sepsis And The Hematology Laboratory

An affordable, widely available test can impact today`s biggest healthcare challenge.

Sepsis, the inflammatory response to infection, is quickly becoming one of the biggest healthcare problems worldwide. No matter the perspective one takes, the numbers are staggering. Currently the number of diagnosed cases per year in the United States is at least 750,000; some estimates surpass one million. Worldwide mortality estimates are as high as 20 percent, and thus we are dealing with one of the biggest drivers of mortality in modern medicine. Sepsis kills nearly as many people as heart attack, HIV, and breast cancer combined.

Viewed from the perspective of health economics, the average in-hospital cost per case is approximately $20,000 dollars, and yearly estimates of sepsis-related expenses in the U.S. alone exceed $20 billion.

There Is Now A Sixth Taste – And It Explains Why We Love Carbs

As any weight-watcher knows, carb cravings can be hard to resist. Now there’s evidence that carbohydrate-rich foods may elicit a unique taste too, suggesting that “starchy” could be a flavour in its own right.

It has long been thought that our tongues register a small number of primary tastes: salty, sweet, sour and bitter. Umami – the savoury taste often associated with monosodium glutamate – was added to this list seven years ago, but there’s been no change since then.

However, this list misses a major component of our diets, says Juyun Lim at Oregon State University in Corvallis. “Every culture has a major source of complex carbohydrate. The idea that we can’t taste what we’re eating doesn’t make sense,” she says.

Mmm… taste that delicious starch
Jonathan Knowles/Getty

Spike In Teen Obesity Explained By Decreased Calorie Burn In Puberty

The rise in obesity rates during adolescence may be due to a substantial fall of calories burned during the rapid growth phase of puberty, finds a new study by the University of Exeter Medical School in the United Kingdom.

According to the Centers for Disease Control and Prevention, around 20 percent of adolescents age 12-19 years are obese in the United States. Obese teenagers are more likely to have prediabetes, a condition in which blood glucose levels indicate a high risk for the development of diabetes.

Adolescents who are obese are also at a greater risk for bone and joint problems, sleep apnea, social and psychological problems, and they are more likely to have risk factors for cardiovascular diseases, such as high cholesterol or high blood pressure.

During puberty, the number of calories girls and boys burn while at rest plummets.

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