How to Increase Laboratory Accuracy with Direct HbA1c Testing !

HbA1c:

Diabetes is a global epidemic affecting in the region of 425 million people according to the International Diabetes Federation. Worryingly, this figure is on the rise with forecasts suggesting diabetes will affect up to 629 million people globally by 2045. Such a dramatic increase highlights the fundamental need for better disease management. When we look at the worldwide prevalence of diabetes, the United States is one of the most prominent countries affected.

HbA1c - an important biomarker for diabetes management and control !

HbA1c, also known as hemoglobin A1c or glycated hemoglobin, is an important blood test used to determine how well diabetes is being controlled. It develops when hemoglobin, a protein within the red blood cells that carries oxygen throughout the body, joins with glucose in the blood, becoming “glycated.” The concentration of HbA1c in the blood of diabetic patients increases with rising blood glucose levels and is representative of the mean blood glucose level over the preceding six to eight weeks. HbA1c can therefore be described as a long-term indicator of diabetic control, unlike blood glucose which is only a short-term indicator of diabetic control. It is recommended that HbA1c levels are monitored every three to four months.

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Differences between Type 1 and Type 2 Diabetes.

Diabetes, or diabetes mellitus (DM), is a metabolic disorder in which the body cannot properly store and use sugar.

It affects the body's ability to use glucose, a type of sugar found in the blood, as fuel. This happens because the body does not produce enough insulin, or the cells do not correctly respond to insulin to use glucose as energy.

Insulin is a type of hormone produced by the pancreas to regulate how blood sugar becomes energy. An imbalance of insulin or resistance to insulin causes diabetes.

Diabetes is linked to a higher risk of cardiovascular disease, kidney disease, vision loss, neurological conditions, and damage to blood vessels and organs.

There is type 1, type 2, and gestational diabetes. They have different causes and risk factors, and different lines of treatment.

This article will compare the similarities and differences of types 1 and 2 diabetes.

People with type 1 diabetes will require supplemental insulin on an

ongoing basis. People with type 2 will likely only need this for the later

stages of the condition. A healthcare specialist will be able to test

a patient for diabetes, even if type 2 diabetes shows no symptoms.

Read more: Differences between Type 1 and Type 2 Diabetes.

Source: MedicalNewsToday

How Does Alcohol Affect My Blood Sugar Levels?

It is not uncommon to enjoy a glass of wine with dinner or to have drinks after work with friends. Alcohol consumption is very prevalent in the United States.

According to the National Institute on Alcohol Abuse and Alcoholism, in 2014:

• 87.6 percent of people age 18 and older reported drinking alcohol at some point in their lifetime
• 71 percent reported drinking in the past year
• 56.9 percent reported drinking in the past month

For many people, a glass of alcohol here and there does not pose a problem. For those with certain health conditions such as diabetes, however, alcohol can affect blood sugar levels and pose a health risk. It is important for them to understand what alcohol is and how it affects blood sugar levels.

Read more: How Does Alcohol Affect My Blood Sugar Levels?

The way that alcohol affects the body differs from person to person. People with diabetes and other
blood sugar-related illnesses must be extremely careful when consuming alcohol. Cocktails and
mixed drinks are full of sugar, so should be avoided by people with blood sugar problems.

Source: MedicalNewsToday

MCQ 9. A Nucleoside is a Structural Subunit of Nucleic Acids

MCQ 9. A nucleoside is a structural subunit of nucleic acids that are the heredity-controlling components of all living cells.

What does it consist of?

a. Nitrogenous base
b. Purine or pyrimidine base + sugar
c. Purine or pyrimidine base + phosphorous
d. Purine or pyrimidine base + sugar + phosphorous

e. Purine + pyrimidine base + sugar + phosphorous

Answers

Fat vs Carbs: What’s Really Worse for Your Health?

The traditional balanced diet may be way out of whack. To fight obesity and diabetes, doctors and nutritionists are embracing diets that were once called fads.

“PEOPLE have told me what I do is dangerous. They have walked away from me at meetings,” says David Unwin, a doctor practising in Southport, UK. Unwin suggests to his patients with type 2 diabetes or who want to lose weight that they do the opposite of what official health advice recommends. He advises them to stop counting calories, eat high-fat foods – including saturated fats – and avoid carbohydrates, namely sugar and starch. Telling people to avoid sugar is uncontroversial; the rest is medical heresy.

Read more: Fat vs Carbs: What’s Really Worse for Your Health?

Source: NewScientist

Diabetes once a problem of the rich, now belongs to the poor too.

As the global diabetes rate soared over the past quarter-century, the affected population transformed: What was once predominantly a rich-country problem has become one that disproportionately affects poorer countries.

That's one of the many conclusions of the World Health Organization's first global report on the chronic disease. Worldwide, diabetes rates nearly doubled, from 4.7 percent in 1980 to 8.5 percent in 2014. Roughly one in 12 people living in the world today have the disease, which has spread dramatically.

“If we are to make any headway in halting the rise in diabetes, we need to rethink our daily lives: To eat healthily, be physically active, and avoid excessive weight gain,” Dr. Margaret Chan, WHO Director-General, said in a statement. “Even in the poorest settings, governments must ensure that people are able to make these healthy choices and that health systems are able to diagnose and treat people with diabetes.”

Read more: Diabetes once a problem of the rich, now belongs to the poor too.

A woman fills a syringe as she prepares to give herself an injection of insulin.

Source: Reed Saxon/AP