Melanoma May Be Stoppable With Drug That Halts Cancer Cell Proliferation

A drug already being tested in people as a treatment for cancer appears to show great promise in halting melanoma skin cancer. The drug - called pevonedistat - works in a way differently than intended and could also be effective against other cancers.

So says a new study from the University of Virginia School of Medicine in Charlottesville that was published in the journal EBioMedicine.

Lead researcher Tarek Abbas, assistant professor of radiation oncology, says:

"In fact, the drug is very effective on all melanomas, including those for which an effective therapeutic is lacking."

Melanoma is an aggressive skin cancer that develops when melanocytes - the cells that give skin its color - mutate and become cancerous.

Read more: Melanoma May Be Stoppable With Drug That Halts Cancer Cell Proliferation

Melanoma is an aggressive skin cancer that develops when cells that give skin its color mutate and
become cancerous. The researchers say they have found a drug that may stop the cancer progressing.

Source: MedicalNewsToday

Enlarged Prostate: Molecular Mechanism Clue May Explain Link To Inflammation

A new study reveals an important molecular clue about how inflammation may lead to prostate enlargement or benign prostatic hyperplasia. The researchers believe their discovery may also lead to ways of overcoming resistance to androgen-targeted treatment for the condition.

Enlarged prostate or benign prostatic hyperplasia (BPH) is a common condition in older men where the prostate gland is enlarged and not cancerous.

As the prostate gland enlarges, it presses against and pinches the urethra, the tube that allows urine to leave the bladder. Also, the bladder wall gradually thickens and the bladder may get weaker and lose the ability to empty completely.

Read more: Enlarged Prostate: Molecular Mechanism Clue May Explain Link To Inflammation

Enlarged prostate or benign prostatic hyperplasia (BPH) is a common condition in older men.

Source: medicalnewstoday