Biomedical Laboratory Science

ShareThis

Monday, April 18, 2016

Rapid Detection of Urinary Biomarkers with Novel Optical Device

A compact optical device has been developed that can rapidly and sensitively detect biomarkers in urine and has promise for developing simple point-of-care diagnostics of cancer and other diseases.

Micro ribonucleic acids (miRNAs) are a newly discovered class of short, about 19 to 24 nucleotides in length, fragments of noncoding RNAs that are useful biomarkers for diagnosing various diseases, including cardiac disease and some cancers. Since they are surprisingly well preserved in fluids such as urine and blood, their detection is well suited to a rapid, point-of-care method.

Bioengineers at the Agency for Science, Technology and Research (Singapore) have devised a silicon photonic biosensor that can detect tiny changes in the phase of a light beam caused by hybridization between an immobilized DNA probe and target miRNAs in a sample. A laser beam travels through a waveguide, which splits into two arms: a sensing arm in which the light interacts with the sample and a reference arm.


Image: Schematic diagram of the MZI biosensor system for miRNA detection.
(a) TEM image of the cross section of a silicon nitride slot wave guide; SEM images of
(b) a strip-slot wave guide mode converter and (c) a silicon nitride grating coupler.
(d) Image of MZI biosensor platform

1 comment:

  1. I was diagnosed with stage 3 breast cancer in August 2010. A valuable friend told me about Dr. Itua Herbal Center in West Africa. She gave me her phone number and email address. I quickly contacted him to guarantee that his herbal medicines will heal my cancer and I will heal forever I said OK.I ask him what is the healing process, he asks me to pay the fees I did and within 7 working days he sent me the herbal medicine and then he asked me I told my friend Gomez about the herbal drug so that he gave me to go and drink it.So after drinking for two weeks, I was cured, I am so grateful and I promise that I will do it I recommend to anyone who has cancer and that that I am doing. Herbal medicine Dr. Itua makes me believe that there is hope for people with Parkinson's disease, schizophrenia, scoliosis, bladder cancer, colorectal cancer, breast cancer, kidney cancer. , Leukemia, lung cancer, skin cancer, uterine cancer, prostate cancer Fibromyalgia,
    Fibrodysplasia Syndrome, Epilepsy,Sclerosis sickness, Dupuytren's Disease, Diabetes, Celiac Disease, Angiopathy, Ataxia, Arthritis, Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Lupus, Adrenocortic Carcinoma.Asthma, Allergic Diseases.HIV Help, Bladder cancer,Brain cancer,Esophageal cancer,Gallbladder cancer,Gestational trophoblastic disease,Head and neck cancer,Hodgkin lymphoma
    Intestinal cancer,Liver cancer,Melanoma,Mesothelioma,Multiple myeloma,Neuroendocrine tumors
    Non-Hodgkin lymphoma,Cervical Cancer,Oral cancer,Ovarian cancer,Sinus cancer,Soft tissue sarcoma,Spinal cancer,Stomach cancer
    ,Testicular cancer,Throat cancer,Meniere's disease,Thyroid Cancer,Vaginal cancer,Vulvar cancer
    HIV Aids, Herpes, Disease Chronic inflammatory, Memory disorder,
     Here is his contact information ...... [Email ... drituaherbalcenter@gmail.com. Whatsapp ... + 2348149277967]

    ReplyDelete

Related Posts Plugin for WordPress, Blogger...

AddToAny