Estradiol Patches Now Fully Subsidized: What Is Their Place In The Treatment Of Menopausal Symptoms?

Transdermal estradiol patches (25, 50 and 100 microgram Estradot brand patches) are now fully subsidised, without the need for Special Authority approval, as a form of menopausal hormone therapy (MHT) for the treatment of menopausal symptoms. From 1 January, 2017, a 75 microgram patch will also be available.

Previously, Climara brand 50 and 100 microgram patches were available through Special Authority funding. The Special Authority funding for these medicines was removed on 1 October, 2016, and Climara brand 50 and 100 microgram patches will be delisted from 1 January, 2017. Patients who are currently using Climara patches and require ongoing treatment will need to switch to Estradot brand patches.

Read more: Estradiol Patches Now Fully Subsidized: What Is Their Place In The Treatment Of Menopausal Symptoms?

Source: bpac

Breast Cancer: The Body of Knowledge Grows

Scientists’ understanding of the genetics/genomics of breast cancer continues to grow; a revolution is underway both in terms of categorizing breast cancers and targeting treatment that will be effective in individual cases. New perspectives are being offered on the interpretation of biopsies, too. Here is a round-up of some very recent studies.

Genetic variants alter cells’ response to estrogen

An international study of almost 120,000 women has newly identified five genetic variants affecting risk of breast cancer, all of which are believed to influence how breast cells respond to the female sex hormone estrogen.

Estrogen acts as a trigger, binding to a molecule known as an estrogen receptor in most breast cells and triggering a cascade of signals that cause the cell to behave normally. However, the estrogen receptor is switched off in some cells and these do not respond to the hormone.

Read more: Breast Cancer: The Body of Knowledge Grows

Source: MedicalLaboratoryObserver

Menopause: Symptoms, Causes and Treatments

The menopause marks the time in a woman's life when her menstruation stops and she is no longer fertile (able to become pregnant).

In the UK the average age for the menopause is 52 (National Health Service), while in the USA it is 51 (National Institute of Aging). About one fifth of women in India experience menopause before the age of 41.

The menopause is a normal part of life - it is a milestone, just like puberty - it is not a disease or a condition. Even though it is the time of the woman's last period, symptoms may begin many years earlier. Some women may experience symptoms for months or years afterwards.

Read more: Menopause: Symptoms, Causes and Treatments

Women going through the menopause may experience problems with focusing and learning.

Source: medicalnewstoday