Gene Mutation 'Hotspots' Linked to Better Cancer Outcomes

Patients with the mutations tended to survive longer and had tumors more susceptible to aggressive treatment.

Breast cancer patients with groups of mutations clustered in their genome have better outcomes than patients without them, researchers found in a recent study.

More than half of breast cancer patients have clusters of genetic mutations called kataegis, and their cancer tends to be less invasive, offering better opportunities for effective treatment, according to researchers at the University of California San Diego.

Read more: Gene Mutation 'Hotspots' Linked to Better Cancer Outcomes

Although researchers are unsure of how the clusters of genetic mutations called kataegis occur,
but cancer patients who have them in tumors tend to respond better to treatment and have better
outcomes, according to a recent study.

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Autistic people have higher gene mutations but lesser risk to cancer

While people with autism have more cancer-related gene mutations, they are at lower risk for developing the disease. This is the conclusion of a new study by researchers from the University of Iowa.

Autism is a developmental disorder characterized by problems with social interaction, communication and repetitive behaviors.

In the US, it is estimated that 1 in 68 children have autism, most of whom are boys.

Study leader Dr. Benjamin Darbro, of the University of Iowa Carver College of Medicine, notes that the finding of a genetic link between autism and cancer is not a new discovery; previous research has established that the conditions share risk genes.

Read more: Autistic people have higher gene mutations but lesser risk to cancer

Autism patients have more mutations in cancer-related genes, but they are at lower risk of developing
cancer than those without autism.

Source: medicalnewstoday