The death of brain cells in Parkinson's disease is likely a result of stress in their endoplasmic reticulum or protein-folding machinery rather than just a general failure of their mitochondria or powerhouses.
So conclude researchers from the University of Leicester in the United Kingdom, who report their findings, based on research conducted in fruit flies, in the journal Cell Death and Disease.
Dr. Miguel Martins, who heads a group in the MRC Toxicology Unit at Leicester, says:
"This research challenges the current held belief the Parkinson's disease is a result of malfunctioning mitochondria."
Source: medicalnewstoday
