Biomedical Laboratory Science

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Showing posts with label Regenerate. Show all posts
Showing posts with label Regenerate. Show all posts

Monday, August 8, 2016

Could Regrowing Limbs be a Medical Possibility?

Although the idea of regrowing an amputated limb sounds like science fiction, some experts believe that, one day, it could become science fact. According to recent findings, the answers may be glimpsed in genes that we share with our very distant relatives.

Although humans cannot regrow lost limbs, there is a range of species that can regenerate lost appendages.

These animals include echinoderms, such as starfish and sea cucumbers; amphibians, including the axolotl and newt; and certain fish species.

Although these animals are considered to be far-removed from humanity, because we all evolved from a joint ancestor, we still share large quantities of genetic information.

And, humanity's ability to regenerate has not been completely lost. Although it is now limited to regrowing fingertips and healing wounds, similar genetic mechanisms are thought to be at work.


Limb generation may be a long way down the road, but genetic studies give a glimmer of hope.
Axolotls can regrow entire limbs with ease.

Thursday, May 5, 2016

Vitamin D Could Repair Nerve Damage in Multiple Sclerosis

A protein activated by vitamin D could be involved in repairing damage to myelin in people with multiple sclerosis (MS), according to new research from the University of Cambridge. The study, published today in the Journal of Cell Biology, offers significant evidence that vitamin D could be a possible treatment for MS in the future.

Researchers, from the MS Society Cambridge Centre for Myelin Repair, identified that the ‘vitamin D receptor’ protein pairs with an existing protein, called the RXR gamma receptor, already known to be involved in the repair of myelin, the protective sheath surrounding nerve fibres.

By adding vitamin D to brain stem cells where the proteins were present, they found the production rate of oligodendrocytes (myelin making cells) increased by 80%. When they blocked the vitamin D receptor to stop it from working, the RXR gamma protein alone was unable to stimulate the production of oligodendrocytes.


Neuron with oligodendrocyte and myelin sheath (edited)
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