Biomedical Laboratory Science

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Friday, May 6, 2016

Breast milk hormones found to impact bacterial development in infants' guts

Intestinal microbiome of children born to obese mothers significantly different from those born to mothers of healthy weight

A new study finds that hormones in breast milk may impact the development of healthy bacteria in infants' guts, potentially protecting them from intestinal inflammation, obesity and other diseases later in life.

The study, published Monday in the American Journal of Clinical Nutrition, examines the role of human milk hormones in the development of infants' microbiome, a bacterial ecosystem in the digestive system that contributes to multiple facets of health.

"This is the first study of its kind to suggest that hormones in human milk may play an important role in shaping a healthy infant microbiome," said Bridget Young, co-first author and assistant professor of pediatric nutrition at CU Anschutz. "We've known for a long time that breast milk contributes to infant intestinal maturation and healthy growth. This study suggests that hormones in milk may be partly responsible for this positive impact through interactions with the infant's developing microbiome."

Researchers found that levels of insulin and leptin in the breast milk were positively associated with greater microbial diversity and families of bacteria in the infants' stool.


A new study examined the role of human milk hormones in the development of infants' microbiome

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