Biomedical Laboratory Science

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Showing posts with label Pre-analytical. Show all posts
Showing posts with label Pre-analytical. Show all posts

Thursday, November 3, 2016

Standardization And Implementation of Lab Policies Ensure Hemostasis Sample Quality

How many of us remember the tilt-tube method for basic hemostasis testing? Fortunately, today’s instruments have automated most of these manual steps. However, until recently, assuring sample quality in the pre-analytical phase of testing had remained a manual process and had been difficult to implement and standardize.

Several questions must be considered when evaluating the integrity of a hemostasis sample: Is the sample tube under-filled? Is the sample hemolyzed, icteric, or lipemic? If so, do the levels of the interferent impact the testing results? Is there a clot in the sample?

All labs have policies on sample acceptance and rejection. Inappropriate rejection of acceptable samples—requiring redraw—directly impacts patient care, patient satisfaction, and cost. Failing to reject inappropriate samples can lead to the reporting of erroneous results, impacting the quality of patient care and associated cost. Let’s take a look at the most common pre-analytical quality issue culprits.



Friday, April 29, 2016

The Brain-to-Brain Loop in Molecular Oncology Laboratory Testing

Various Methods Allow Clinical Laboratories to Maximize Their Efficiency and Usefulness

The delineation of a brain-to-brain loop in clinical laboratory testing first published in 1981 has never been more pertinent. Its subsequent development and current application in clinical molecular oncology in 2016 can make all the difference.

This discussion focuses on the factors that drive the ordering of a lab test and the many components thereof, itemizes pre- and post-analytic causes of diagnostic error, and recommends how a laboratory can help ensure the usefulness of the entire process.

Just as a chain is no stronger than its weakest link, a loop that isn’t closed is (obviously) still open.

Technical and laboratory workers tend naturally to define their work by their technical products and procedures, as well they should. In clinical laboratory testing, that tends to be the step called “analysis.”

The success or failure of an “analysis” may well depend upon the pre- and post-analytic phases at least as much as the analysis itself.


Source: DepositPhotos
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