These Building Blocks Could Be Valuable Tools for Research
Amino acids are important building blocks for protein synthesis and are also intermediary metabolites that fuel biosynthetic reactions, thus playing a dual role in cellular metabolism. Accurate quantification of L-amino acids in body fluids or purified samples may provide valuable information for diagnostic and basic research studies.
Cellular Roles of Amino Acids in Cancer and Neurobiology
Cancer cells have altered metabolism and are known for their metabolic abnormalities. One example is the Warburg effect, in which there is increased glycolytic activity even in the presence of oxygen. Cancer cells depend on a high rate of aerobic glycolysis for continued growth and survival.
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Figure 1. Glutamine and the metabolism of other amino acids as targets for cancer therapy.
[Int J Mol Sci 2015;16:22830–22855; doi:10.3390/ijms160922830]
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Source: genengnews
