A two-gene panel was shown to differentiate between viral and bacterial infections in children with fevers with 95-100% accuracy.
Since clinical features do not reliably distinguish bacterial from viral infection, many children worldwide receive unnecessary antibiotic treatment, while bacterial infection is missed in others. To solve this problem, investigators at Imperial College London (United Kingdom) sought to identify a blood RNA expression signature that could distinguish bacterial from viral infection in febrile children.
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| An example of an approximately 40,000 probe spotted RNA microarray with enlarged inset to show detail (Photo courtesy of Wikimedia Commons). |
Source: labmedica
