The risk of aggressive serous or serous-like endometrial cancer may be higher for women with a BRCA1 gene mutation, even after undergoing risk-reducing surgery involving the removal of the fallopian tubes and ovaries. This is the finding of a new study published in JAMA Oncology.
However, the study found that a mutated BRCA1 gene did not increase women's overall risk of uterine cancer if they had undergone the risk-reducing procedure, called risk-reducing salpingo-oophorectomy (RRSO).
RRSO is the surgical removal of the fallopian tube and ovaries, and it is sometimes recommended for women who are at high risk of breast or ovarian cancers as a result of BRCA1 or BRCA2 gene mutations.
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| Researchers say women with a BRCA1 mutation are at higher risk for aggressive endometrial cancer, even after undergoing risk-reducing surgery. |
Source: medicalnewstoday.
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