Biomedical Laboratory Science

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Tuesday, July 19, 2016

Antibiotic Resistance Raising the Specter of 'Untreatable Gonorrhea'

A new federal health surveillance study says gonorrhea is becoming resistant to azithromycin - one of the duo of antibiotics recommended for treating the sexually transmitted disease in the United States.

The study, from the Centers for Disease Control and Prevention (CDC), is published in the agency's Morbidity and Mortality Weekly Report (MMWR).

Gonorrhea is a sexually transmitted disease (STD) caused by a bacterium called Neisseria gonorrhoeae that infects the genitals, rectum, and throat.

Gonorrhea occurs in both men and women, and is one of the most common STDs in the U.S. It is especially common among young people of 15-24 years of age.


The CDC say the growing threat of untreatable gonorrhea, together with rising rates of disease,
means preventing new infections is more important than ever.

Simplify Residual Renal Function (RRF) Estimation

Determination and monitoring of RRF has been a long-standing challenge for laboratories. Unreliable, labor-intensive urine collection and complex equations have made accurate measurement and reporting problematic.

Siemens N Latex BTP assay is the first marker to accurately, reliably, and simply estimate RRF status with one serum sample.


"BTP provides a promising blood measure of RRF that could facilitate existing recommendations to
integrate regular assessment of RKF.

Sunday, July 17, 2016

If You Want to Study in the United States

Book 1: Undergraduate Study

Undergraduate Study — how to choose and apply to U.S. bachelor’s and associate degree programs, plus information on technical and vocational educational opportunities in the United States.

Undergraduate Study is one of a series of four introductory booklets produced by the U.S. Department of State to provide objective and practical advice to prospective international students and scholars on studying in the United States.



Science Behind Power Naps

With a very busy schedule and too much on our plate, we are not getting enough sleep nowadays. Sleep deprivation is very bad for the health and is giving rise to a number of diseases nowadays. Diseases like heart problems, fluctuations in sugar levels, high and low blood pressures and thyroid issues have become very common in sleep deprived individuals. This is where power naps can help.

When you sleep during the day between 1 PM and 4 PM for a period lasting between ten to thirty minutes, it is known as a power nap. If you sleep longer than thirty minutes, you might develop sleep inertia, a groggy feeling. You should also not sleep later than 4 PM as then you will find it difficult to sleep at night.



Source: boldsky

Compounds Detected in Breath Samples Specific to Ovarian Cancer

Diagnosing cancer today usually involves various imaging techniques, examining tissue samples under a microscope, or testing cells for proteins or genetic material. 

In search of safer and less invasive ways to tell if someone has cancer, analyzing breath and defining specific profiles of compounds in breath samples is under investigation, but translating these exhaled disease fingerprints into a meaningful diagnosis has required a large number of sensors, which makes them impractical for clinical use.


Schematic representation of analysis of breath samples for the diagnosis of ovarian cancer

Fluctuating Serum Aspartate Aminotransferase Activity in a Complicated Pregnancy

Clinical Case Study
A 29-year-old para 0 gravida 2 woman with a history of infertility and spontaneous abortion presented to her local hospital at 9 weeks gestation with severe nausea and vomiting. Symptoms persisted for 10 weeks, leading to the diagnosis of hyperemesis gravidarum and treatment with intravenous fluids (3 times/week) and Zofran.

At 8 weeks gestation, laboratory tests were unremarkable with the exception of increased aspartate aminotransferase (AST)5 measured at a regional reference laboratory [105 U/L; reference interval (RI), 10 – 40 U/L]. AST continued to be monitored at the same laboratory, peaking at 132 U/L (9 weeks gestation) and gradually declining to 38 U/L by 19 weeks gestation.


uqccr/hepcarepharmacy
Source: clinchem

Side Effects of Alzheimer's Gene Visible in Child Brain Development

Certain genes increase the risk of developing Alzheimer's disease. The side effects of the most common of these genes, apolipoprotein E, may be evident as early as in childhood, a study finds.

Genetic risks are just one of the factors that may increase or decrease a person's chances of developing Alzheimer's disease (AD), along with age and family history.

While the symptoms of the rarer early-onset AD - representing less than 5 percent of people with the disease - can appear from the age of 30, the symptoms of the more common type, late-onset AD, is apparent over the age of 65.

This study, published in the online issue of Neurology, finds that the effects of the AD gene apolipoprotein E (APOE) may possibly be seen before the age of 20.


Studying genes in childhood that increase the risk of developing Alzheimer's disease may possibly
help experts develop ways of delaying the disease.

Tips on How Not to Blow Your Patients Vein

One of the major functions of a nurse is to insert IV lines on patients. This should be done perfectly but experienced nurses may still encounter or face problems like a blown vein. In order to minimize patient discomfort and overall productivity of a nurse, here are some useful tips to lessen or eliminate those errors.
  1. Assess the veins– Look for a good vein by palpating the arm or area with your fingers. Choose the larger and straight vein as this will be able to accommodate large bore catheters.
  2. Go for the correct size of the catheter– To be safe and avoid a blown small vein otherwise, use a small one. Gauge 22 is ideal for adult patients while gauges 22-26 catheters for pediatric patients.


Source: nursingguide

Saturday, July 16, 2016

MCQ 10. The glycoprotein hormones are a family of cystine rich proteins


MCQ 10. The glycoprotein hormones are a family of cystine rich proteins consisting of an alpha and beta subunit, and are characterized by their heavy glycosylation.

Which of the following is a glycoprotein hormone?
a. Cortisol  
b. Growth hormone releasing hormone (GHRG)
c. Thyrotropin releasing hormone (TRH) 
d. Thyrotropin (TSH)
e. Oxytocin

Answers

Does Going to the Hospital Make You Sicker?

During a hospital stay, people usually hope to have a medical condition treated effectively so they can recover fully, go home and stay home. But it's not uncommon for a hospitalization to lead to a new health problem that's serious enough to require hospital readmission within 30 days.

The phenomenon, dubbed "post-hospital syndrome" by Dr. Harlan Krumholz, a cardiologist and professor of medicine at the Yale School of Medicine, is roughly defined as an acquired, transient period of increased risk for illness after a hospital stay, one that leads to re-hospitalization.


You could find yourself back in the hospital – because of the hospital (Getty Images).
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