Biomedical Laboratory Science

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Monday, September 12, 2016

Five Signs Of Hormone Imbalance You Shouldn't Ignore

Be vigilant of these five signs of hormonal imbalance, from poor sleep to chronic acne.

Hormones affect everyone from birth to death, yet the word has a negative connotation. Most people use "raging hormones" to explain teenage angst, or "hormonal" to describe PMS in women, and maybe for good reason: hormonal symptoms have a lot to do with our lifestyle, diet, and environment.

Hormone problems are very common, so feeling like we're experiencing a hormonal balance, or a fluctuation in hormones, is not unusual.




Melanoma May Be Stoppable With Drug That Halts Cancer Cell Proliferation

A drug already being tested in people as a treatment for cancer appears to show great promise in halting melanoma skin cancer. The drug - called pevonedistat - works in a way differently than intended and could also be effective against other cancers.

So says a new study from the University of Virginia School of Medicine in Charlottesville that was published in the journal EBioMedicine.

Lead researcher Tarek Abbas, assistant professor of radiation oncology, says:

"In fact, the drug is very effective on all melanomas, including those for which an effective therapeutic is lacking."

Melanoma is an aggressive skin cancer that develops when melanocytes - the cells that give skin its color - mutate and become cancerous.


Melanoma is an aggressive skin cancer that develops when cells that give skin its color mutate and
become cancerous. The researchers say they have found a drug that may stop the cancer progressing.

Ten Interesting Facts About Body Temperature

Body temperature can be affected by various circumstances

In order to maintain a healthy metabolic process, our enzymes need to be functioning at a certain optimal temperature – 37°C or 98.6°F. Body temperature is the balance between heat loss and heat production.

Fortunately, we are able to maintain a healthy body temperature regardless of external outside temperature. For instance, putting a jacket on if you are cold or taking off your sweater if you feel yourself getting warm.





Sunday, September 11, 2016

'We Can Completely Reverse Alcohol Dependence'

Scientists have discovered a way to entirely remove the urge to drink alcohol compulsively in an animal model. The researchers hope that, with enough funding, a solution to this age-old problem might be on the horizon.

Alcohol has been brewed and consumed by humans for almost 10,000 years.

In 2014, 87.6 percent of Americans over the age of 18 reported that they had consumed alcohol at least once in their life.

Although commonly available, it is an incredibly addictive substance. In the United States, an estimated 16.3 million adults over the age of 18 have an alcohol use disorder, and around 88,000 people die from alcohol-related causes annually.

For these reasons, thousands of researchers are dedicated to understanding the causes behind a compulsive need to drink alcohol and ways in which it might be curbed.


Could alcoholism finally be on the way out?

Sepsis And The Hematology Laboratory

An affordable, widely available test can impact today`s biggest healthcare challenge.

Sepsis, the inflammatory response to infection, is quickly becoming one of the biggest healthcare problems worldwide. No matter the perspective one takes, the numbers are staggering. Currently the number of diagnosed cases per year in the United States is at least 750,000; some estimates surpass one million. Worldwide mortality estimates are as high as 20 percent, and thus we are dealing with one of the biggest drivers of mortality in modern medicine. Sepsis kills nearly as many people as heart attack, HIV, and breast cancer combined.

Viewed from the perspective of health economics, the average in-hospital cost per case is approximately $20,000 dollars, and yearly estimates of sepsis-related expenses in the U.S. alone exceed $20 billion.


There Is Now A Sixth Taste – And It Explains Why We Love Carbs

As any weight-watcher knows, carb cravings can be hard to resist. Now there’s evidence that carbohydrate-rich foods may elicit a unique taste too, suggesting that “starchy” could be a flavour in its own right.

It has long been thought that our tongues register a small number of primary tastes: salty, sweet, sour and bitter. Umami – the savoury taste often associated with monosodium glutamate – was added to this list seven years ago, but there’s been no change since then.

However, this list misses a major component of our diets, says Juyun Lim at Oregon State University in Corvallis. “Every culture has a major source of complex carbohydrate. The idea that we can’t taste what we’re eating doesn’t make sense,” she says.


Mmm… taste that delicious starch
Jonathan Knowles/Getty

Spike In Teen Obesity Explained By Decreased Calorie Burn In Puberty

The rise in obesity rates during adolescence may be due to a substantial fall of calories burned during the rapid growth phase of puberty, finds a new study by the University of Exeter Medical School in the United Kingdom.

According to the Centers for Disease Control and Prevention, around 20 percent of adolescents age 12-19 years are obese in the United States. Obese teenagers are more likely to have prediabetes, a condition in which blood glucose levels indicate a high risk for the development of diabetes.

Adolescents who are obese are also at a greater risk for bone and joint problems, sleep apnea, social and psychological problems, and they are more likely to have risk factors for cardiovascular diseases, such as high cholesterol or high blood pressure.


During puberty, the number of calories girls and boys burn while at rest plummets.

Saturday, September 10, 2016

Short-Chain Fatty Acids In Control Of Body Weight And Insulin Sensitivity

The connection between the gut microbiota and the etiology of obesity and cardiometabolic disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the cardiometabolic phenotype by fermenting indigestible dietary components and thereby producing short-chain fatty acids (SCFA). These SCFA are not only of importance in gut health and as signaling molecules, but might also enter the systemic circulation and directly affect metabolism or the function of peripheral tissues.

In this Review, we discuss the effects of three SCFA (acetate, propionate and butyrate) on energy homeostasis and metabolism, as well as how these SCFA can beneficially modulate adipose tissue, skeletal muscle and liver tissue function.


Short-Chain Fatty Acids (SCFA) and liver function.

Friday, September 9, 2016

Why Cockroach Milk Is the New Health Obsession

Health freaks will go to extreme lengths in the name of nutrients (and staying one step ahead of the trend), but I'm not afraid to say it: The latest "superfood" is just plain gross.

Taking stomach-churning to a whole new level is cockroach milk, which is comprised of the nutrient-rich milk crystals found inside the Pacific Beetle cockroach. This species uses said protein crystals as food for cockroach infants, but new research suggests that it could be beneficial to humans, too, as it's one of the most nourishing and highly caloric substances on the planet. It boasts four times as much protein as cow's milk, but also contains essential amino acids that promote cell growth, lipids that keep our bodies healthy, and sugars that fuel energy.


How Reliable Is The Glycemic Index?

Individual response to glycemic index values vary so much that it may not be useful in indicating blood sugar response, says research published in the American Journal of Clinical Nutrition.

The glycemic index (GI) of a food indicates the speed with which blood sugar can be expected to rise after a person eats it. Each food gets a score out of 100 on the index, for example, 40 for baked beans.

Glycemic load is a measure that applies the GI to a portion of food. The glycemic load for a 150-gram serving of baked beans would be 6.

GI is used to help people with diabetes to control their blood sugar. Some food labels carry GI measurements. More recently, a number of popular diets have been based on GI. Lists are available for people to check the GI and glycemic load of different foods.


People use the glycemic index as a guide to suitable foods, but is it a valid measure?
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