Short-Chain Fatty Acids In Control Of Body Weight And Insulin Sensitivity

The connection between the gut microbiota and the etiology of obesity and cardiometabolic disorders is increasingly being recognized by clinicians. Our gut microbiota might affect the cardiometabolic phenotype by fermenting indigestible dietary components and thereby producing short-chain fatty acids (SCFA). These SCFA are not only of importance in gut health and as signaling molecules, but might also enter the systemic circulation and directly affect metabolism or the function of peripheral tissues.

In this Review, we discuss the effects of three SCFA (acetate, propionate and butyrate) on energy homeostasis and metabolism, as well as how these SCFA can beneficially modulate adipose tissue, skeletal muscle and liver tissue function.

Read more: Short-Chain Fatty Acids In Control Of Body Weight And Insulin Sensitivity

Short-Chain Fatty Acids (SCFA) and liver function.

Source: NatureReviewsEndocrinology

Why Cockroach Milk Is the New Health Obsession

Health freaks will go to extreme lengths in the name of nutrients (and staying one step ahead of the trend), but I'm not afraid to say it: The latest "superfood" is just plain gross.

Taking stomach-churning to a whole new level is cockroach milk, which is comprised of the nutrient-rich milk crystals found inside the Pacific Beetle cockroach. This species uses said protein crystals as food for cockroach infants, but new research suggests that it could be beneficial to humans, too, as it's one of the most nourishing and highly caloric substances on the planet. It boasts four times as much protein as cow's milk, but also contains essential amino acids that promote cell growth, lipids that keep our bodies healthy, and sugars that fuel energy.

Read more: Why Cockroach Milk Is the New Health Obsession

Source: msn.com/en-ca/health/wellness

Watch: Cockroach Milk - The Next Superfood?

How Reliable Is The Glycemic Index?

Individual response to glycemic index values vary so much that it may not be useful in indicating blood sugar response, says research published in the American Journal of Clinical Nutrition.

The glycemic index (GI) of a food indicates the speed with which blood sugar can be expected to rise after a person eats it. Each food gets a score out of 100 on the index, for example, 40 for baked beans.

Glycemic load is a measure that applies the GI to a portion of food. The glycemic load for a 150-gram serving of baked beans would be 6.

GI is used to help people with diabetes to control their blood sugar. Some food labels carry GI measurements. More recently, a number of popular diets have been based on GI. Lists are available for people to check the GI and glycemic load of different foods.

Read more: How Reliable Is The Glycemic Index?

People use the glycemic index as a guide to suitable foods, but is it a valid measure?

Source: medicalnewstoday

Validating the Performance of Body Fluid Specimens

In health care, the analysis of body fluids plays an important role in the diagnosis and management of a wide variety of conditions. Traditionally, clinical laboratorians have provided analysis of body fluid specimens without question while also recognizing the sometimes difficult work that goes into their collection. As standards for method validation and laboratory developed tests (LDTs) evolve, the analysis of body fluids is receiving increased attention from both laboratories and regulatory bodies.

The clinical laboratory’s overarching goal is to ensure accurate test results from all specimens. Therefore, it is the responsibility of every laboratory to investigate the analytical performance of the tests performed on the various fluid types accepted and to provide a context for result interpretation.

Read more: Validating the Performance of Body Fluid Specimens

Source: medlabmag

Serum Albumin Levels Associated with Mortality in Hemodialysis Patients

Serum albumin is commonly used as a proxy for nutritional status, as well as a marker of inflammation and a low serum albumin concentration is not only indicative of protein energy wasting in dialysis patients, but it is also a powerful predictor of the mortality risk in this population.

Several clinical conditions are associated with low serum albumin levels in dialysis patients, including infectious and inflammatory diseases, fluid overload, inadequate dialysis, severe co-morbidity, and taste change. Therefore, regular monitoring of serum albumin levels is useful for predicting outcomes in dialysis patients.

Read more: Enlarged Prostate: Molecular Mechanism Clue May Explain Link To Inflammation

The Hitachi 7600–210 modular clinical biochemistry analyzer (Photo courtesy of Hitachi).

Source: labmedica

Enlarged Prostate: Molecular Mechanism Clue May Explain Link To Inflammation

A new study reveals an important molecular clue about how inflammation may lead to prostate enlargement or benign prostatic hyperplasia. The researchers believe their discovery may also lead to ways of overcoming resistance to androgen-targeted treatment for the condition.

Enlarged prostate or benign prostatic hyperplasia (BPH) is a common condition in older men where the prostate gland is enlarged and not cancerous.

As the prostate gland enlarges, it presses against and pinches the urethra, the tube that allows urine to leave the bladder. Also, the bladder wall gradually thickens and the bladder may get weaker and lose the ability to empty completely.

Read more: Enlarged Prostate: Molecular Mechanism Clue May Explain Link To Inflammation

Enlarged prostate or benign prostatic hyperplasia (BPH) is a common condition in older men.

Source: medicalnewstoday

Two-Gene Panel Differentiates between Pediatric Bacterial and Viral Infections

A two-gene panel was shown to differentiate between viral and bacterial infections in children with fevers with 95-100% accuracy.

Since clinical features do not reliably distinguish bacterial from viral infection, many children worldwide receive unnecessary antibiotic treatment, while bacterial infection is missed in others. To solve this problem, investigators at Imperial College London (United Kingdom) sought to identify a blood RNA expression signature that could distinguish bacterial from viral infection in febrile children.

Read more: Point-Of-Care Hemoglobin Testing: Methods And Relevance To Combat Anemia

An example of an approximately 40,000 probe spotted RNA microarray with enlarged inset to show
detail (Photo courtesy of Wikimedia Commons).

Source: labmedica

Cesarean Delivery May Increase Risk of Childhood Obesity

Children born by cesarean delivery may have an increased risk of becoming obese, compared with their siblings born by vaginal delivery, says study. This finding may have significant implications for the almost 1.3 million cesarean births per year in the United States.

Cesarean delivery is the most common U.S. surgical procedure and accounts for one third of deliveries nationwide.

The most common risk to children born via cesarean delivery is respiratory problems, while increasing evidence suggests children may also have an increased risk of other adverse health outcomes as adults.

Read more: Cesarean Delivery May Increase Risk of Childhood Obesity

Cesarean delivery can increase a child's risk of obesity into adulthood, study finds.

Source: medicalnewstoday

How To Prevent and Treat Fatty Liver

I have a Fatty Liver- Now what?

Many of my clients have digestive issues and think it is to do with a food they are eating. Sometimes they opt for allergy testing, others get blood work or an ultrasound done to see if there are any serious problems.

More and more clients are been diagnosed with a fatty liver and ask me now what do I do?

What is a fatty liver?

A fatty liver is the result of excess fat in the liver. This fat builds up when a person’s diet exceeds the amount of fat their body can handle. Having a fatty liver can lead to fatty liver disease, which then leads to chronic illnesses. Many who are overweight, have belly fat, are insulin resistant, pre- diabetic and who crave sugars and starches are likely have a fatty liver. Yet many who are ultimately healthy and not overweight are finding they to, have a fatty liver.

Read more: How To Prevent and Treat Fatty Liver

Source: justnaturallyhealthy

Antibiotics In Early Life Could Raise Children's Food Allergy Risk

Infection in the first year of life can be deadly for an infant, and antibiotic treatment is often the first port of call. But such treatment may have a downside; new research from the University of South Carolina finds early antibiotic exposure could raise a child's risk of food allergies.

While the study did not investigate the reasons behind this association, the researchers say it is likely down to changes in gut microbiota as a result of antibiotic treatment.

Lead author Dr. Bryan Love, of the Department of Clinical Pharmacy and Outcomes Sciences at the South Carolina College of Pharmacy, and colleagues report their results in the journal Allergy, Asthma & Clinical Immunology.

Previous research has suggested that changes to the composition of gut bacteria in early life can have negative implications for health, and antibiotics are known to do just that.

Read more: Antibiotics In Early Life Could Raise Children's Food Allergy Risk

Early antibiotic exposure could raise children's risk of food allergies.

Source: medicalnewstoday